Applied biopharmaceutics and pharmacokinetics / Leon Shargel and Andrew B. C. Yu.
Material type:
TextPublication details: New York : Appleton-Century-Crofts, c1980Description: vii, 245 pages ; 24 cmISBN: 0838502067Subject(s): BIOPHARMACEUTIC | PHARMACOKINETICSLOC classification: RM 301.4 .S53 1980
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LRC - Annex | National University - Manila | Pharmacy | Relegation Room | GC RM 301.4 .S53 1980 (Browse shelf (Opens below)) | c.1 | Available | NULIB000008162 |
Includes bibliographical references and index.
1. Review of mathematical fundamentals -- 2. Rates and orders of reactions -- 3. Introduction to pharmacokinetics -- 4. One-compartment open model -- 5. Multicompartment models -- 6. Biopharmaceutic aspects of drug products -- 7. Pharmacokinetics of drug absorption -- 8. Bioavailability and bioequivalence -- 9. Drug clearance -- 10. Hepatic elimination of drugs -- 11. Protein binding of drugs -- 12. Intravenous infusion -- 13. Multiple dosage regimens -- 14. Nonlinear pharmacokinetics -- 15. Application of pharmacokinetics in clinical situations -- 16. Dosage adjustment in renal disease -- 17. Relationship between pharmacokinetic parameters and pharmacologic response.
The main objective of this book is to present basic concepts in practical biopharmaceutics and pharmacokinetics to students with at least a minimal skill in mathematics.
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