Biopharmaceutics and clinical pharmacokinetics / Milo Gibaldi
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TextPublication details: Philadelphia, Pennsylvania : Lea & Febiger, c1991Edition: Fourth editionDescription: x, 406 pages : illustrations ; 27 cmISBN: - 812113462
- RM 301.4 .G53 1991
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National University - Manila | LRC - Main General Circulation | Pharmacy | GC RM 301.4 .G53 1991 (Browse shelf(Opens below)) | c.1 | Available | NULIB000015277 |
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| GC RC 46 .H37 2018 vol.2 Harrison's principles of internal medicine / | GC RC 630 .J64 2008 Fluids and electrolytes demystified / | GC RC 71 .C87 2013 Current medical diagnosis and treatment 2013 / | GC RM 301.4 .G53 1991 Biopharmaceutics and clinical pharmacokinetics / | GC RM 301.4 .M65 2010 c.1 Molecular biopharmaceutics : aspects of drug characterisation, drug delivery and dosage form evaluation / | GC RM 301.4 .M65 2010 c.2 Molecular biopharmaceutics : aspects of drug characterisation, drug delivery and dosage form evaluation / | GC RM 301.4 .S53 1999 Applied biopharmaceutics & pharmacokinetics / |
Includes bibliographical references and index.
Introduction to pharmacokinetics -- Compartmental and noncompartmental pharmacokinetics -- Gastrointestinal absorption--biologic considerations -- Gastrointestinal absorption--physicohemical considerations -- Gastrointestinal absorption--role of the dosage forms -- Nonoral medication -- Prolonged-release medication -- Bioavailability -- Drug concentration and clinical response -- Drug disposition--distribution -- Drug disposition--elimination -- Pharmacokinetic variability-- body weight, age, sex, and generic factors -- Pharmacokinetic variability--disease -- Pharmacokinetic variability--drug interactions -- Individualization and optimization of drug dosing regiments
This updated introduction to the clinical applications of pharmacokinetics looks at gastrointestinal absorption, prolonged release medication, and drug disposition. The effects of disease, weight, age, sex and genetic factors on pharmacokinetic variability and drug response are detailed. Bioequivalence and regulatory considerations for generic drug.
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