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The organic chemistry of drug design and drug action / Richard B. Silverman and Mark W. Holladay

By: Silverman, Richard B [author]Contributor(s): Holladay, Mark W [co-author]Material type: Text

TextPublication details: San Diego, CA Academic Press, c2014Edition: Third editionDescription: xvii, 517 pages : color illustrations ; 29 cmISBN: 9780123820303Subject(s): PHARMACEUTICAL CHEMISTRY | BIOORGANIC CHEMISTRY | MOLECULAR PHARMACOLOGYLOC classification: RS 403 .S55 2014

Contents:

Introduction -- Lead discovery and lead modification -- Receptors -- Enzymes -- Enzyme inhibition and inactivation -- Dna-interactive agents -- Drug resistance and drug synergism -- Drug metabolism -- Prodrugs and drug delivery systems.

Summary: The Organic chemistry of drug design and drug action, Third edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition reflects significant changes in the process of drug design over the last decade. It preserves the successful approach of the previous editions while including significant changes in format and coverage.

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Item type	Current library	Home library	Collection	Shelving location	Call number	Copy number	Status	Date due	Barcode
Books	LRC - Main	National University - Manila	Pharmacy	General Circulation	GC RS 403 .S55 2014 (Browse shelf (Opens below))	c.1	Available		NULIB000013679

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Previous	GC RS 403 .P73 2004 Practical pharmaceutical chemistry : part two /	GC RS 403 .P73 2015 The practice of medicinal chemistry /	GC RS 403 .Q33 2011 Textbook of inorganic pharmaceutical and medicinal chemistry /	GC RS 403 .S55 2014 The organic chemistry of drug design and drug action /	GC RS 403 .S56 2006 c.1 Martin's physical pharmacy and pharmaceutical sciences : physical chemical and biopharmaceutical principles in the pharmaceutical sciences /	GC RS 403 .S56 2006 c.2 Martin's physical pharmacy and pharmaceutical sciences : physical chemical and biopharmaceutical principles in the pharmaceutical sciences /	GC RS 403 .S56 2017 Martin's physical pharmacy and pharmaceutical sciences /	Next

Includes index.

Introduction --
Lead discovery and lead modification --
Receptors --
Enzymes --
Enzyme inhibition and inactivation --
Dna-interactive agents --
Drug resistance and drug synergism --
Drug metabolism --
Prodrugs and drug delivery systems.

The Organic chemistry of drug design and drug action, Third edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows the reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition reflects significant changes in the process of drug design over the last decade. It preserves the successful approach of the previous editions while including significant changes in format and coverage.

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