Includes index.

Drugs and drug targets --
an overview --
Drug targets : structure and function --
Protein structure and function --
Enzymes: structure and function --
Receptors: structure and function --
Receptors and signal transduction --
Nucleic acids: structure and function --
Pharmacodynamics and pharmacokinetics --
Enzymes as drug targets --
Receptors as drug targets --
Nucleic acids as drug targets --
Miscellaneous drug targets --
Pharmacokinetics and related topics --
Statins --
Drug discovery, design, and development --
Drug discovery: finding a lead --
Drug design: optimizing target interactions --
Drug design: optimizing access to the target --
Getting the drug to market --
The design of ACE inhibitors --
Artemisinin and related antimalarial drugs --
The design of oxamniquine --
Tools of the trade --
Combinatorial synthesis --
Computers in medicinal chemistry --
Quantitative structure-activity relationships (QSAR) --
De novo design of a thymidylate synthase inhibitor --
Selected topics in medicinal chemistry --
Antibacterial agents --
Antiviral agents --
Anticancer agents --
Cholinergics, anticholinergics, and anticholinesterases --
Drugs acting on the adrenergic nervous system --
Opioid analgesics --
Antiulcer agents --
Steroidal anti-inflammatory agents --
Design of a novel antidepressant.

Renowned for its clear and accessible writing style, An Introduction to Medicinal Chemistry 6th edition is widely regarded as the leading undergraduate text in this area. Complete coverage of the subject is augmented by extensive pedagogical support and opportunities for students to hone their problem solving skills.