Includes bibliographical references and index.

Nucleic acids and proteins -- Gene expression and epigenetics -- Nucleic acid extraction methods -- Resolution and detection of nucleic acids -- Analysis and characterization of nucleic acids and proteins -- Nucleic acid amplification -- Chromosomal structure and chromosomal mutations -- Gene mutations -- DNA sequencing -- DNA polymorphisms and human identification -- Detection and identification of microorganisms -- Molecular detection of inherited diseases -- Molecular oncology -- DNA-based tissue typing -- Quality assurance and quality control in the molecular laboratory.

Meet the challenges of this rapidly expanding field
Molecular diagnostics continues to grow in importance in the clinical laboratory. This respected text will prepare your students with a grounding in the fundamental principles of molecular biology. current methods, and their clinical applications.

With a focus on the application of molecular concepts to diagnostic purposes, the text explains and illustrate the use and interpretation of molecular-based assays in patient care. Now with an expanded discussion of nucleic acid sequencing, with added emphasis on next generation sequencing (NGS), and updated coverage of proteomics and mass spectrometry applications, your students will have the most current information available today.