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Foye's principles of medicinal chemistry / David A. Williams and Thomas L. Lemke

By: Williams, David A [author]Contributor(s): Lemke, Thomas L [co-author]Material type: Text

TextPublication details: Philadelphia : Lippincott Williams & Wilkins, c2002Edition: Fifth editionDescription: xii, 1,114 pages : illustrations ; 29 cmISBN: 9780683307375Subject(s): PHARMACEUTICAL CHEMISTRYLOC classification: RS 403 .W55 2002

Contents:

Introduction: Origins of Medicinal Chemistry / William O. Foye -- pt. I. Principles of Drug Discovery -- Overview: Drug Design and Development: A Perspective / Michael Williams -- 1. Natural Products / Alice M. Clark -- 2. Drug Design and Relationship of Functional Groups to Pharmacologic Activity / James J. Knittel and Robin M. Zavod -- 3. Molecular Modeling and Drug Design / Eric Billings -- 4. Receptors and Drug Action / Timothy J. Maher and David A. Johnson -- 5. Drug Design Through Enzyme Inhibition / Stephen G. Kerr -- 6. Peptide and Protein Drugs / Michael Mokotoff -- 7. Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics / Sunil Jambhekar -- 8. Drug Metabolism / David A. Williams -- 9. U.S. Drug Regulation: An Overview / Douglas J. Pisano -- pt. II. Pharmacodynamic Agents -- Overview: Drug Receptors: A Perspective / David J. Triggle -- 10. Drugs Affecting Cholinergic Neurotransmission / Danny L. Lattin and E. Kim Fifer -- 11. Drugs Affecting Adrenergic Neurotransmission / Robert Griffith -- 12. Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission / Richard A. Glennon and Malgorzata Dukat -- 13. Local Anesthetics / Matthias C. Lu -- 14. Volatile Anesthetics / Timothy J. Maher -- 15. Hypnotics / William Soine -- 16. Antiseizure Drugs / Barbara W. Leduc -- 17. Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents / Raymond G. Booth and John L. Neumeyer -- 18. Hallucinogens, Stimulants, and Related Drugs of Abuse / Richard A. Glennon -- 19. Opioid Analgesics / David S. Fries -- 20. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents / Raymond G. Booth and John L. Neumeyer -- 21. Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs / Ahmed S. Mehanna -- 22. Diuretics / Gary O. Rankin.

Summary: Aims to meet the changing curricula of medicinal chemistry courses. This title emphasises on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. It features over 700 illustrations.

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Item type	Current library	Home library	Collection	Shelving location	Call number	Copy number	Status	Date due	Barcode
Books	LRC - Main	National University - Manila	Pharmacy	General Circulation	GC RS 403 .W55 2002 (Browse shelf (Opens below))	c.1	Available		NULIB000004020

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Includes index.

Introduction: Origins of Medicinal Chemistry / William O. Foye --
pt. I. Principles of Drug Discovery --
Overview: Drug Design and Development: A Perspective / Michael Williams --
1. Natural Products / Alice M. Clark --
2. Drug Design and Relationship of Functional Groups to Pharmacologic Activity / James J. Knittel and Robin M. Zavod --
3. Molecular Modeling and Drug Design / Eric Billings --
4. Receptors and Drug Action / Timothy J. Maher and David A. Johnson --
5. Drug Design Through Enzyme Inhibition / Stephen G. Kerr --
6. Peptide and Protein Drugs / Michael Mokotoff --
7. Physicochemical and Biopharmaceutical Properties of Drug Substances and Pharmacokinetics / Sunil Jambhekar --
8. Drug Metabolism / David A. Williams --
9. U.S. Drug Regulation: An Overview / Douglas J. Pisano --
pt. II. Pharmacodynamic Agents --
Overview: Drug Receptors: A Perspective / David J. Triggle --
10. Drugs Affecting Cholinergic Neurotransmission / Danny L. Lattin and E. Kim Fifer --
11. Drugs Affecting Adrenergic Neurotransmission / Robert Griffith --
12. Serotonin Receptors and Drugs Affecting Serotonergic Neurotransmission / Richard A. Glennon and Malgorzata Dukat --
13. Local Anesthetics / Matthias C. Lu --
14. Volatile Anesthetics / Timothy J. Maher --
15. Hypnotics / William Soine --
16. Antiseizure Drugs / Barbara W. Leduc --
17. Psychotherapeutic Drugs: Antipsychotic and Anxiolytic Agents / Raymond G. Booth and John L. Neumeyer --
18. Hallucinogens, Stimulants, and Related Drugs of Abuse / Richard A. Glennon --
19. Opioid Analgesics / David S. Fries --
20. Drugs Used to Treat Neuromuscular Disorders: Antiparkinsonian and Spasmolytic Agents / Raymond G. Booth and John L. Neumeyer --
21. Cardiac Agents: Cardiac Glycosides, Antianginal, and Antiarrhythmic Drugs / Ahmed S. Mehanna --
22. Diuretics / Gary O. Rankin.

Aims to meet the changing curricula of medicinal chemistry courses. This title emphasises on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. It features over 700 illustrations.

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