Concepts in clinical pharmacokinetics /
William J. Spruill [and four others]
- Sixth edition.
- Bethesda, MD : American Society of Health-System Pharmacists, c2014.
- x, 284 pages : color illustrations ; 28 cm.
Includes index.
Lesson 1. introduction to pharmacokinetics and pharmacodynamics -- Lesson 2. basic pharmacokinetics -- Lesson 3. half-life, elimination rate, and auc -- Lesson 4. intravenous bolus administration, multiple drug administration, and steady-state average concentrations -- Lesson 5. relationships of pharmacokinetic parameters and Intravenous intermittent and continuous infusions -- Lesson 6. two-compartment models -- Lesson 7. biopharmaceutics: absorption -- Lesson 8. drug distribution and protein binding -- Lesson 9. drug elimination processes -- Lesson 10. nonlinear processes -- Lesson 11. pharmacokinetic variation and model-independent relationships -- Lesson 12. aminoglycosides -- Lesson 13. vancomycin -- Lesson 14. theophylline -- Lesson 15. phenytoin and digoxin
Concepts in Clinical Pharmacokinetics has helped thousands of students and practitioners through five editions by simplifying a complex subject. The authors have thoroughly reviewed, revised, and redesigned the text to enhance the reader's grasp of the material. This 6th Edition offers a superior approach to understanding pharmacokinetics through extensive use of clinical correlates, figures, and questions and answers