TY - BOOK AU - Burger, Alfred TI - Burger's medicinal chemistry and drug discovery: volume I: principles and practice SN - 471575615 AV - RS 403 .B87 1995 PY - 1995/// CY - New York PB - Wiley KW - PHARMACEUTICAL CHEMISTRY N1 - Information Sciences in Drug Discovery -- Drug Absorption, Distribution and Elimination -- Drug Biotransformations -- Drug Allergy --Structural Determinants of Carcinogenicity and Mutagenicity -- Molecular Recognition in Drug Design and Discovery -- Drug Receptors -- Drug-Target Binding Forces -- Chemical Information Computing Systems in Drug Discovery -- Quantitative Analysis of Structure-Activity Relationships -- Molecular Modelling in Drug Design -- Mass Ligand Screening in Drug Discovery -- Approach to the Rational Design of Enzyme Inhibitors -- Guidelines for Analog Design -- Natural Products as Leads for Pharmacueticals N2 - This updated edition covers the latest methods of drug discovery, as well as topics of current interest, such as computational chemistry and peptidomimetrics ER -