Includes index.

Preface: Hepatocellular Carcinoma: Its Past, Present, and Future -- The Global Epidemiology of Hepatocellular Carcinoma: Present and Future -- Anatomic Pathology of Hepatocellular Carcino: Impact on Prognosis and Response to Theraphy -- The Role of Oncogenic Viruses in the Pathogenesis of Hepatocellular Carcinoma -- Insulin Resistance and Other Metabolic Risk Factors in the Pathogenesis of Hepatocellular Carcinoma -- Diagnosis of Hepatocellular Carcinoma: Role of Tumor Markers and Liver Biopsy -- Hepatocelullar Carcinoma: Molecular and Genomic Guideline for the Clinician -- Hepatocellular Carcinoma: Screening and Staging -- Imaging of Hepatocellular Carcinoma: Partical Guide to Differential Diagnosis -- Conventional Surgical Treatment of Hepatocellular Carcinoma -- Laparoscopic Liver Liver Resection in the Treatment of Hepatocellular Carcinoma -- Liver Transplantation for Hepatocellular Carcinoma: Expanding Frontiers and Building Bridges -- Locoregional Theraphy for Hepatocellular Carcinoma -- Systematic Theraphy in Hepatocellular Carcinoma -- Liver Neoplasia in Children.

Dr. Adrian Reuben updates one of the most highly requested topics in liver disease by inviting highly distinguished authors to address the important aspects of diagnosis and treatment of hepatocelluar carcinoma. State-of-the-art issues are addressed, including the role of oncogenic viruses, molecular and genetic guidelines, and screening and staging. Dr. Reuben, himself, concludes the issue with an important article on an agorithmic approach to diagnosis and treatment: Resect, Ablate, Replace or Intoxicate?