000			03107nam a2200229Ia 4500
003			NULRC
005			20250520102853.0
008			250520s9999 xx 000 0 und d
020			_a781734819
040			_cNULRC
050			_aRS 403 .W55 2004
245		0	_aWilson and Gisvold's textbook of organic medicinal and pharmaceutical chemistry / _cedited by John H. Block and John M. Beale Jr.
250			_aEleventh edition.
260			_aPhiladelphia, Pennsylvania : _bLippincott Williams & Wilkins, _cc2004
300			_axiv, 991 pages : _billustrations ; _c29 cm.
504			_aIncludes index.
505			_aIntroduction / John H. Block and John M. Beale, Jr. -- Physicochemical properties in relation to biological action / John H. Block -- Combinatorial chemistry / Douglas R. Henry -- Metabolic changes of drugs and related organic compounds / Stephen J. Cutler and John H. Block -- Prodrugs and drug latentiation / Forrest T. Smith and C. Randall Clark -- Biotechnology and drug discovery / John M. Beale, Jr. -- Immunobiologicals / John M. Beale, Jr. -- Anti-infective agents / John M. Beale, Jr. -- Antimalarials / John H. block -- Antibacterial antibiotics / John M. Beale, Jr. -- Antiviral agents / John M. Beale, Jr. -- Antineoplastic agents / William A. Remers -- Agents for diagnostic imaging / Tim B. Hunter, T. Kent Walsh, Jack N. Hall. Central nervous system depressants / Eugene I. Isaacson -- Central nervous system stimulants / Eugene I. Isaacson -- Adrenergic agents / Rodney L. Johnson -- Cholinergic drugs and related agents / George H. Cocolas and Stephen J. Cutler -- Diuretics / Daniel A. Koechel -- Cardiovascular agents / Stephen J. Cutler and george H. Cocolas -- Local anesthetic agents / Gareth Thomas -- Histamine and antihistaminic agents / Thomas N. Riley and Jack DeRuiter -- Analgesic agents / Robert E. Willette -- Steroids and therapeutically related compounds / Philip J. Proteau -- Prostaglandins, leukotrienes, and other eicosanoids / Thomas J. Holmes, Jr. -- Proteins, enzymes, and peptide hormones / Stephen J. Cutler and Horace G. Cutler -- Vitamins and related compounds / Gustavo R. Ortega, Michael J. Deimling, and Jaime N. Delgado -- An introduction to the medicinal chemistry of herbs / John M. Beale, Jr. -- Computational chemistry and computer assisted drug design / J. Phillip Bowen.
520			_aThis textbook integrates the chemical and pharmaceutical principles necessary to understand structure-activity relationships and the molecular mechanisms of drug action. In 28 chapters, medicinal chemists, pharmacists, and other scientists discuss topics like combinatorial chemistry, biotechnology, immunobiologicals, anti- infective agents, antimalarials, antibiotics, antiviral agents, antineoplastic agents, diagnostic imaging, depressants, stimulants, adrenergic, diuretics, cardiovascular agents, local anesthetics, steroids, peptide hormones, vitamins, herbs, and computational chemistry and computer-assisted drug design.
650			_aPHARMACEUTICAL CHEMISTRY
700			_aBlock, John H. ;Beale, John M. Jr. _eeditor;editor
942			_2lcc _cBK
999			_c17459 _d17459